Determination of polychlorinated dibenzo-p-dioxins and furans in food samples by gas chromatography-triple quadrupole mass spectrometry (GC-MS/MS) and comparison with gas chromatography-high resolution mass spectrometry (GC-HRMS)
نویسندگان
چکیده
Although gas chromatography–triple quadrupole mass spectrometry (GC-MS/MS) has been applied to the determination of polychlorinated dibenzo-p-dioxins and furans (PCDD/Fs) in various food samples, there is insufficient evidence evaluate its equivalence with chromatography–high resolution (HRMS). In present study, two GC-MS/MS instruments different ion sources (advanced electron ionization [EI] atmospheric pressure chemical [APCI]) were evaluated for detecting trace levels PCDD/Fs foods. GC-EI-MS/MS GC-APCI-MS/MS showed good linear relationships 17 (0.01–200 ng/mL, R2 > 0.999), relative standard deviations response factors 3–18%. The limit quantitation range was 0.005–0.101 ng/mL 0.006–0.201 GC-EI-MS/MS. capabilities methods reference materials real samples. Statistical analyses that toxic equivalents (TEQs) comparable those obtained GC-HRMS, had sensitivity, repeatability, reproducibility. No difference found between results from techniques GC-HRMS when concentrations greater than 10−2 pg/g. suggest total TEQ 0.57 pg TEQ/g (lipid weight) or 0.052 (wet weight), could be used as a complementary approach GC-HRMS. Both have similar selectivity, stability HRMS confirmation analysis animal
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ژورنال
عنوان ژورنال: Journal of Food Composition and Analysis
سال: 2023
ISSN: ['0889-1575', '1096-0481']
DOI: https://doi.org/10.1016/j.jfca.2022.104947